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doi: 10.1016/j.jff.2020.104172 421 DengHLiuJXiaoYWuJLJiaoR

10.3390/ijms22105213 5 AliN.RashidS.NafeesS.HasanS

A very high dose of 30 g shows little difference between males and females

Homocysteine reduction: NAC has been shown to lower plasma homocysteine levels by 11.5% at a dose of 1,800 mg/day in patients with hyperhomocysteinemia, likely through a disulfide exchange reaction (Ventura et al., Pharmacology, 2003) [66]

Anti-Parkinson drugs like dopamine (DA) agonists, levodopa, carbidopa, monoamine oxidase type B inhibitors and anticholinergics are used to replace DA in the current treatment model

[71] Another double-blind, placebo-controlled trial found that the test group comprising 65 patients who received 5% n-acetylcysteine gel for 8 weeks had significantly reduced the number of comedones compared to patients in the control group (34 patients) who received only placebo