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In a diabetic rat model, small interfering RNAs (siRNAs) targeting specific lncRNAs may attenuate DPN by decreasing the production of inflammatory factors

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Endothelial cells within the lymphatic system facilitate the transport of CSF, macromolecules, and immune cells from the CSF to the cervical lymph nodes, playing a key role in clearing metabolic waste products and modulating the immune response (17, 84, 107, 108)

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