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Target Protein Sequence: MCAARLAAAA AAAQSVYAFS ARPLAGGEPV SLGSLRGKVL LIENVASLSG TTVRDYTQMN ELQRRLGPRG LVVLGFPCNQ FGHQENAKNE EILNSLKYVR PGGGFEPNFM LFEKCEVNGA GAHPLFAFLR EALPAPSDDA TALMTDPKLI TWSPVCRNDV AWNFEKFLVG PDGVPLRRYS RRFQTIDIEP DIEALLSQGP SCA

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10.1006/mcne.1996.0020 19 BansalR.LakhinaV.RemediosR.ToleS

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In particular, topiramate may control the flow of glutamate and cysteine through System Xc-, which could impact GSH synthesis and improve the ability of GPX4 to change harmful lipid hydroperoxides into safe lipid alcohols

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