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Clin Toxicol (Phila)

Treatment of vitamin B12 deficiency is the only indication for prescribing of hydroxocobalamin or cyanocobalamin in primary care

In this study, B12 levels were 244 pmol/l or more in all patients at baseline, but in those who improved, B12 levels almost quadrupled, whilst in non-responders B12 levels went up by only 50%

Monitoring deep tendon reflexes helps in evaluating the patients neurological status and identifying any changes or abnormalities that may be indicative of neuropathy or other neurological complications

In our clinical experience at San Diego Acne Clinic, we have never seen B12 help acne, only worsen it

However, for those with inactive disease it may be reasonable to stop at the start of the third trimester, in line with peak foetal development[1]