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Finally, FASN has long been a promising target for anticancer therapy, but so far no drug has proceeded to the clinics [66]

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(2) decreased serotonin storage result from hyperactive platelets and thrombocytopenia

Activation of the NF-B pathway further promotes NLRP3 transcription and inflammatory cytokines such as TNF- and IL-6, impairing renal vascular cells [76, 114]