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Nat Rev Nephrol

This review article will introduce some of the small molecule drugs that are currently receiving significant attention: Orforglipron Orforglipron is an oral small molecule GLP-1RA developed jointly by Eli Lilly and Chia Tai Tianqing Pharmaceutical Group

The findings of DiGregorio et al challenge the classic presentation and argue for increased vigilance

The PIEZO2 mutation causing joint deformities reinforces the notion that abnormalities in proprioception may lead to musculoskeletal deformities [ 160 ]

Thus, the ENS is regarded as a second brain that can directly or indirectly respond to the microbiota and its metabolites influencing cognitive functions through gut bacteria (51)

A systematic review found that sexual dysfunction (including ED) is common in transgender populations, underscoring the need for inclusive research and care