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This drug should be applied with caution in pregnant women, especially during early pregnancy when maximum organogenesis occurs

Moreover, it reveals that possible mechanisms behind this effect might include granulation tissue formation, reepithelialization and deposition of collagen through the ERK1/2 signaling pathway [6] 3

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This process (called titration) gives patients time to adjust to potential side effects

Many medications are often prescribed off-label for conditions that exceed their original FDA approval