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M.KannegantiT.-D.et al (2019)

OReilly S, Hgle T, van Laar JM (2012) T cells in systemic sclerosis: a reappraisal

In part B of the study, which was open label, patients were assigned to receive a single IV infusion of pegadricase alone (0.4 mg/kg) alone, or SEL-212 (0.03, 0.1, 0.15, or 0.3 mg/kg ImmTOR combined with 0.4 mg/kg pegadricase

The corresponding protein is defective in DNA-binding because the insertion has occurred between the first and second zinc cluster

These findings suggest that resveratrol can restore mitochondrial dynamic balance by correcting CCI-induced fission-fusion imbalances