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Mice with a deletion of serine racemase showed reduced levels of brain D-serine and brain-derived neurotrophic factor, and loss of glutamatergic neurotransmission, and consequently had less complex dendrites (Morita et al., 2007

After the induction of inflammation, the degree of joint disease was observed and recorded

76 in which five out of nine patients with previous progression responded to a 4-week KD with partial remission or stable disease as judged by FDG-PET scans

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39,43,46,47,48 Dosages used have ranged from 800 to 2000 mg per day in longer-term studies (212 weeks), with the highest dose seeing the largest reductions in homocysteine

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