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DISCUSSION The debate concerning the possible role of vitamin B 12 in MS is long lasting and several studies with different results have been done since 1950s and early 1960s.[3] Although demyelination is a prominent feature of both MS and B 12 deficiency, these two entities are usually distinguishable based on clinical and pathological characteristics

The consistency of the safety profile across short-term and long-term trials suggests that AOD-9604 does not produce cumulative toxicity or delayed adverse effects that emerge only with chronic administration

The underlying condition is sequenced first per ICD-10-CM guidelines

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AndreescuCEMilojkovicBAHaasdijkEDKramerPDe JongFHKrustAet al

When to worry: Bald patches (not just thinning)