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Search methods, inclusion criteria, effect extraction criteria (more serious outcomes have priority), all individual study data, PRISMA answers, and statistical methods are detailed in Appendix 1

544 While various phenotypic syndromes and their associated gene mutations have been discussed, the genetic and phenotypic heterogeneity of mitochondrial diseases is notably complex

Brighton, UK: Healthline Media UK Ltd

Cells adjacent to the wound formed a migrating front with reduced proliferation and stratification with a surrounding area of highly proliferative cells, reproducing changes seen following excisional wounding of the esophagus in vivo (Fig

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