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Metabolic Reprogramming Mediated by the Mtorc2-IRF4 Signaling Axis is Essential for Macrophage Alternative Activation

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18 When coupled with smaller and more infrequent meals, bile salt secretion into the intestine is decreased, reducing gallbladder motility and triggering the formation of biliary sludge, i.e., crystals or microliths composed of precipitated lipid particles

Taken together, these findings demonstrate that while GSSG is indeed formed during plasma treatment, extensive treatment can cause an over-oxidation of the disulphide bond resulting in the two end products GSNO and GSO 3 H with a strong preference for the latter

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