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When combined with antibiotics, thalidomide lowered TNF- levels, reduced leukocytosis, and alleviated brain pathology, resulting in markedly improved survival in a rabbit model of acute M.tb CNS infection [144]

A significant increase (25%) in microsomal lipid peroxidation was observed in both liver and kidney of diabetic rats (Figure 1C)

Ginseng is available in various forms, including capsules, teas, and extracts

These findings thus provide mechanistic insights into how local periodontal inflammation exacerbates systemic comorbidities and underscore the critical importance of managing local inflammatory diseases