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In another study, an 84-week open-label trial with about 800 participants, people taking CagriSema had an average of 23% weight loss versus about 25 to 26% for tirzepatide (Zepbound) at the highest dose

Use the semaglutide to tirzepatide conversion chart or the reverse conversion chart to find your equivalent starting dose

Rosenstock J, Balas B, Charbonnel B, Bolli GB, Boldrin M, Ratner R, et al

239 In an uncontrolled trial that included 15 women with fibromyalgia, seven of whom had also been diagnosed with chronic fatigue syndrome, treatment with a synbiotic (probiotic/prebiotic combination) for 30 days decreased stress, anxiety, and depression, improved quality of life, and reduced IL-8 levels