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Moreover, abnormal histone changes and altered expression of non-coding RNAs are other factors leading to metastasis and resistance to treatment (Yu et al

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For instance, a recent study revealed that microbial metabolic disorders leading to Th17/Treg imbalance can trigger hepatocyte ferroptosis, potentially explaining the involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease [81]

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