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While ROS are essential for pathogen clearance, excessive and unregulated production leads to widespread cellular and tissue injury (Figure 3) (Mantzarlis et al., 2017)

Short-term use of exogenous ketone supplements increases blood BHBA but leads to increased markers of NLRP3 inflammasome activation including caspase-1 and IL-1 secretion (158)

Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma [J]

Roles of metabolic reprogramming in kidney fibrosis

The FNR-ATTRACT programme supports the national research institutions by expanding their competences in strategic research areas by attracting outstanding young researchers with high potential to Luxembourg

Compounds with biological activity from edible and medicinal fungi are thought to contribute significantly to preserving cognitive performance and protecting neuronal integrity (79)