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In mouse models fed a high fat diet, capsaicin lowers circulating LPS levels, inhibits TLR4 signaling, and suppresses NF-B activation, as reflected by reduced phosphorylation of p65 and inhibitor of B alpha (IB)

Beaugerie, L., Seksik, P., Nion-Larmurier, I., Gendre, J.-P

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Another study suggested that ethacrynic acid also had minimal effects on glucose levels in mildly hypertensive patients (Coni et al., 1974

Although changes were less dramatic compared to animal studies, these specific taxa have been linked to neuroinflammatory processes and gastrointestinal symptoms common in ASD