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Notably, the three-dimensional structure indicates that OsDHAR contains a broad, uncharged cleft between the 2-helix and the 3-helix as the putative binding site for non-native protein folding intermediates for its chaperone-like activity

For viability staining, cells were stained with Cell-ID cisplatin 198Pt (Standard BioTools) at a final concentration of 5 M for 5 min at RT

Nausea is primarily associated with the gastric rhythm disturbance from 3 cycles per minute, which is the normal gastric myoelectrical activity, to either increased activity (tachygastria) or decreased activity (bradygastria) [3]

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