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Graphite furnace atomic absorption spectrometry (GF-AAS, PerkinElmer PinAAcle D900 series, USA) was used for quantitative analysis of the total ruthenium contents from different samples and cells

Upon preincubation of the cancer cells with the antioxidant NAC and subsequent treatment with NP4, the GSH/GSSG ratio was significantly less influenced, reaching a GSH/GSSG ratio of 0.71 (Fig

P.PeuchenS.HealesS

409 Kidney function is also affected by iron overload, putting patients at risk for end-stage renal disease

10.1186/s13041-017-0306-y 502 YolkenR.AdamosM.KatsafanasE.KhushalaniS.OrigoniA.SavageC.et al

Conclusion Multidrug resistance to chemotherapy drugs is one of the main obstacles in human cancer chemotherapy and has prompted intense research into discovering novel and innovative mechanisms that can overcome this barrier