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General measures Because individuals with atypical naevi have a higher lifetime risk of melanoma, they should: Undergo routine skin surveillance, including regular total body skin examinations by a healthcare professional

No further treatment is necessary once a biopsy proven diagnosis of melanotic macule has been rendered

Many forms of pigmentation already exist beneath the surface before somebody ever starts using MT2

In that case, a pragmatic decision needs to be made

Possibly related to chronic minor irritation , chronic biting, friction or sun exposure (for lip lesions), although this link is not consistent

The Food and Drug Administration (FDA) finally approved it as a treatment to boost sexual desire in postmenopausal women in 2019