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In the DRIVE-SHIFT clinical trial of virologically suppressed adults who switched to once-daily DOR/3TC/TDF, slight weight gain consistent with the weight gain expected in people without HIV was observed although approximately 40% of individuals lost weight or had no change in weight through 144 weeks [20]

It is not approved for human or animal use and must not be administered outside controlled in-vitro research environments

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AOD-9604 also inhibits lipogenesis, the synthesis of new fat, adding a second metabolic angle

In western medicines viewpoints, PHN is due to disturbance in local and dermatomal nerves