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Assessment of urolithin A effects on muscle endurance, strength, inflammation, oxidative stress, and protein metabolism in male athletes with resistance training: an 8-week randomized, double-blind, placebo-controlled study

Notably, treatment with glucagon-like peptide-1 receptor agonists (GLP-1-RA) over two years resulted in a 28% reduction in plasma GDF-15 levels compared to lifestyle advice alone, suggesting a potential role for GDF-15 as a marker of therapeutic response (148)

MASLD and HTN have reached epidemic proportions in parallel to obesity

Oral administration of allicin to mice lowered ROS production and prevented ROS-induced cardiac hypertrophy by inhibiting pro-inflammatory pathways like mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/glycogen synthase kinase 3 (GSK3) signaling pathways (20)

Role of inflammation in chemical-induced hepatotoxicity

Based on curcumin incubation for a period of 72 h, a considerable up-regulation was noticed in 11 miRNAs while 18 miRNAs were down-regulated, of which miRNA-22 was most up-regulated while miRNA-199a was most down-regulated