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SHK@HA-MPDA effectively inhibited cytoplasmic PKM2 tetramerization and attenuated its nuclear translocation, significantly reducing lactate and ATP production in CT26 cells

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However, VitD supplementation alone failed to reduce IBD severity since its effect was limited by the downregulation of vitamin D receptor (VDR), whose downregulation resulted in damaged autophagy in inflammatory status [101]

Turmeric has curcumin, which is an active compound that helps in enhancing the natural antioxidant defence of the body, including glutathione

Conjugates formed between glutathione and toxic metabolites are further metabolised into cysteinyl-s-conjugates, which have long half-lives in circulation

13,46 Intensive glycemic control significantly reduces the incidence and progression of neuropathy in T1DM and T2DM patients