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Phytosomes as an emerging nanotechnology platform for the topical delivery of bioactive phytochemicals

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In an OGD/R-treated astrocyte-neuron indirect co-culture system, astrocytes in an ischemic state activate the STAT3 signaling pathway, which leads to an upregulation of the lactate-directed glycolytic process and is accompanied by impairment of mitochondrial function

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Colla E, Jensen PH, Pletnikova O, Troncoso JC, Glabe C, Lee MK (2012) Accumulation of toxic alpha-synuclein oligomer within endoplasmic reticulum occurs in alpha-synucleinopathy in vivo

Of interest, mature OL clusters expressing genes suggestive of immune function have been identified, for example supporting an MHC-class II-mediated response 71