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Aromatase mediates the conversion of androstenedione to estrone and testosterone to estradiol (34) , (37)

Microcirculation 6:127140 Jabbour HN, Kelly RW, Fraser HM, Critchley HO (2006) Endocrine regulation of menstruation

For comparison of two groups, the MannWhitney U test (non-parametric data) was applied

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The analysis of the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways was carried out using Enrichment tool of MetaboAnalyst