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While malate was thought to contribute to increased ATP production through the TCA cycle, the review emphasized that these pathways have not yet been verified in human models and that more research is needed (Gonzalez and Trexler, Nutrients )
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ALDH and Cancer ALDH is considered a reliable marker of cancer stem cells (CSCs), which is widely used to enrich CSC subsets from various cell lines and solid tumors [101]
