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In contrast, -LA improved hyperinsulinemia and the higher levels of free fatty acids of the T2DM rats [129], increases antioxidant defense through Nrf2, and reduces inflammation in T2DM (decreases TNF- and Inhibit the expression of NLRP3 and downstream inflammatory factors IL-18 and IL-1) to prevent liver steatosis and relieve HFD-induced liver lipid accumulation in T2DM rats (Table 7)

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As a result, SLNs can carry hydrophilic or hydrophobic drugs and more accurately deliver anticancer drugs

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TB-500 has also been linked to neural regeneration and reduced inflammation in traumatic brain injury models

(2020) 9:e62601

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