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Furthermore, Farrell et al

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Ethacrynic acid (EA) was purchased from Sigma-Aldrich (USA)

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In patients with significant CAD and normal kidney function, and in atherosclerotic Apoe / mice, we found a significant decrease in the glycine to oxalate ratio aligned with downregulated hepatic AGXT

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These findings emphasize the importance of mitophagy in combating inflammation, and justify further examination in glaucoma

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