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A circadian clock in macrophages controls inflammatory immune responses

The small molecule Limonin blocks the PERK-ATF4-CHOP axis to attenuate inflammatory cytokine release (186)

Oxidative microenvironment exerts an opposite regulatory effect on cytokine production by Th1 and Th2 cells

In vitro models demonstrate that high cholesterol content markedly accelerates syn aggregation, suggesting that these microdomains act as nucleation sites for LB formation [225, 226]

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Melittin activates the 5-lipoxygenase pathway in neutrophils, releasing arachidonate and inducing neutrophilia (75, 76)