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Differences between groups were examined for statistical significance by Students t-test unless otherwise stated

J Neurosci 15:183553, PMID: 7891138 Tanaka K (2000) Functions of glutamate transporters in the brain

These results support that the topology of the EHL is unique to the entire Lot DUB family and can be considered a standard characteristic of Lots

More recent studies have shown that regional depletion of glutamine from PDAC tumors stimulates macropinocytosis by activating EGFR/PAK signaling and supplying glutamine via degradation of extracellular proteins in lysosomes 121

doi: 10.3892/ijo.2018.4343

Up to 350 mg per day from supplements appears safe, though exceeding this may cause diarrhea