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According to Pauling, theoretically, valine can be mis-incorporated once for every 5 correct isoleucine amino acids based on the selection predictions for IleRS [22]

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446 Selective serotonin norepinephrine reuptake inhibitors, selective serotonin reuptake inhibitors, and tricyclic antidepressants may be effective treatments for depression in patients with PD, and nonpharmacologic approaches, including repetitive transcranial magnetic stimulation and cognitivebehavioral therapy, may also be useful