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This study complied with the Declaration of Helsinki (revised in 2013) and was approved by the ethics committee of the Third Affiliated Hospital of Kunming Medical University (Yunnan Cancer Hospital) (No

p53-pS15 is involved in regulating cell cycle arrest and apoptosis resistance in keloids Phospho-specific protein microarray was used to investigate the cell signaling profile in fibroblasts from keloid versus those from adjacent skin

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doi:10.1136/annrheumdis-2016-209285 17Fabbrocini G, Panariello L, Caro G, Cacciapuoti S

Another study showed that the GBA1 protein, catalyzing the conversion of glucosylceramide (GlcCer) into ganglioside, is downregulated in HCC tissues and stimulates this signaling pathway by mediating GlcCer reprogramming, thus promoting EMT and enhancing the metastatic capability of HCC