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According to the manufacturer, a solid-state PEF system should have a lifetime of 10 to 20 years, which means that the cost will reduce dramatically after the depreciation period (Kempkes, 2017)

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Am J Hypertens 21(2):219223 Zhang L, Fang Y, Cheng X, Lian Y, Xu H, Zeng Z, Zhu H (2017) TRPML1 participates in the progression of Alzheimers disease by regulating the PPAR/AMPK/Mtorsignalling pathway

However, the latter may be explained by many factors other than resistant parasites, such as low MDA coverage, inadequate dosing, rapid re-infection, and high worm burden 17,18,19,20

Therefore, low glutathione levels can contribute to the inefficiency of methylation, creating a vicious cycle and furthering depleting ones glutathione levels