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3.2 Enhancement of the intestinal barrier The intestinal mucosal barrier comprises four interdependent layersphysical, chemical, immune, and microbialand their integrity is essential for intestinal homeostasis and immune balance (An et al., 2022)

We performed functional enrichment analysis on the identified sub-networks to further clarify the role of these potential complexes in life regulation

In particular, hypoxia imaging has been associated with radiotherapy resistance, while metabolic and acidosis-related imaging signals have been linked to tumour grade, proliferative activity, and early treatment response dynamics (198, 199)