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Ruvolo P, Ma H, Ruvolo V, Mu H, Shober W, Yasuhiro T, Yoshizawa T, Gallardo M, Zhang X, Khoury JD, Cortex JE, Andreeff M , Post SM

Conversely, in cells where NADPH-consuming reactions are active (e.g., fatty acid synthesis, antioxidant defense), the cytosolic concentration of NADPH decreases, while NADP + increases

Conversely, when mitochondrial function is impaired, cells increase glycolytic flux or activate autophagy to recycle nutrients

Mental stress-induced-myocardial ischemia in young patients with recent myocardial infarction: sex differences and mechanisms

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Furthermore, it has been suggested that this effect is mediated by the anti-inflammatory protein annexin A1 (ANXA1), which contributes to reduced barrier permeability by promoting the formation of tight junctions and enhancing the integrity of endothelial cells [39]