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However, an enzyme activity assay performed immediately after purification revealed that very significant AppA activity was recovered from the BL21 (DE3) pLysSRARE strain with co-expression of Erv1p and DsbC

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Taken together, these results not only confirm previous observations of iron accumulation in AMD eyes but also reveal an iron-transferrin imbalance, with the most pronounced effects observed in nascent GA (iRORA)

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