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Early studies revealed that the neuropeptides delivered orally in this way had a pharmacodynamic profile consistent with the reported pharmacology, were rapidly absorbed by the gastrointestinal tract, and reached concentrations several-fold higher than those seen naturally postprandially (128)

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Although it is well-known that exercise is a very active booster of immunity (25), whereas stress strongly alters the immune response (26), this review did not consider such studies as they are outside the scope of this paper

Moreover, the toxicity of the DOX-loaded nanocarrier was higher than free DOX

229 A recent study showed that by coating a carbon layer on the surface of dendritic degradable MSNs, accelerated degradation of MSNs and collapse of the surface carbon layer could be observed with NIR irradiation

This transparency is vital for researchers calculating precise molar concentrations for their experimental models