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The most severe presentation of disease includes rapid and uncontrolled deterioration of patients with onset of septicaemia and necrotising pneumonia, commonly referred to as cepacia syndrome [Citation24]

SFN mitigates TNF-a and IL-22-induced activation of inflammatory pathways and proliferation in HaCaT cells IL-22 is known to bind to the IL-22 receptor on keratinocytes, induce STAT3 phosphorylation, and promote keratinocyte proliferation [25, 26]

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The pathophysiological role of microglia in dynamic surveillance, phagocytosis and structural remodeling of the developing CNS

Abhinit Gupta combines medical expertise with an artistic understanding of facial balance and beauty