Marotto et al., 2020)
For further biological evaluation, co-culture systems and reconstructed skin models should be adopted to screen for the ability of the novel compounds to interfere with the melanogenesis process, especially following stimuli including UV irradiation, exposure to a-MSH or proinflammatory cytokines
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it has been shown that they transport organic ions, mainly glutathione S-conjugates in an ATP-dependent way [109,111], GSSG is another transport substrate for them [112]
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