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Light regulation of enzyme allostery through photo-responsive unnatural amino acids

Reduced Form: Instead of free form glutathione, Setria is in its "reduced form that is in the active state that the body needs for all its functions

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Inhibition of c-Jun can prevent LINE activation and the accumulation of RNADNA hybrids, thereby reducing cGAS-STING pathway activation and alleviating neuronal programmed cell death and inflammation (Guo et al., 2018

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These approaches target the root causes rather than masking symptoms with medication