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Dempster, J

Diagnostic Procedures: 8

It includes NOX15 and dual oxidases 1 and 2, with one NADPH-binding site, one flavin adenine dinucleotide (FAD)-binding site, six transmembrane domains, and four heme-binding histidines [17]

Chronic oxidative stress in synovial T-lymphocytes of patients with RA results from intracellular ROS production (mainly H 2 O 2 ) (194), and ROS may be involved in destructive pathological events of RA