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2020;94:e114

HYPOPHYSIOTROPIC HORMONES AFFECTING GH RELEASE GHRH GHRH was originally isolated from a pancreatic tumor taken from a patient that presented with acromegaly and somatotroph hyperplasia (309)

To further validate this relationship, we constructed GCLC knockdown vectors (sh group) and overexpression vectors (OE group) and transfected them into rat neural astrocytes for experimental analysis