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World J Emerg Surg 2023;18:23

Current Medicinal Chemistry, 17(3), 312-328

PMID: 37838174 Microbiol Spectr2022 Aug 31;10(4):e0091722

The premise underlying the leaky gut hypothesis is that physiologic stressors such as anxiety, intensive exercise, or dietary components such as emulsifiers increase intestinal mucosal paracellular permeability, enhancing entry of pathogenic bacteria and bacterial toxins into the systemic circulation, provoking systemic inflammation and triggering numerous diseases

The most notable adverse events with ketamine are psychiatric events of dissociation, derealization, depersonalization, and perceptual disturbances [66]

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