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Statistics show that about two-thirds of the 1,200 mitochondrial proteins are located in the matrix, where the major matrix AAA proteases (such as LONP and CLPP) play an important role in the protein folding homeostasis control mechanism of mitochondria

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If there was an important water polo tournament in the 1980s and early 90s, Billish-Fitter was likely there

However, a disadvantage of these small molecules is their uncontrolled toxicity, which results in severe side effects

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The main difference comes down to one critical factor: absorption