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289 Neutrophils are generally accepted to have limited chemokine receptor expression, consisting mainly of the CXC group

On the other hand, high levels of ROS accelerate the cell death and impair the wound healing by derailing the cell and molecular mechanisms

These compounds are prone to rapid metabolism or degradation, leading to inadequate induction in specific tissues or potential toxicity in non-target sites

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However, the dynamic regulation of genes, especially how stress-inducible genes are timely epi-regulated by histone methylation remains largely unclear