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The reference range problem is the most urgent failure

Research Priorities Priority studies should include rigorous human PK (multiple routes, dose proportionality), double blind placebo controlled dose ranging Phase II trials for a single indication (e.g

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Some drugs are protected by patents and are supplied by only one company

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19 Recognising gout and initiating effective treatment early in the clinical course is essential for addressing these disparities and the associated impact on other aspects of life, e.g