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The FDA evaluation found insufficient evidence to establish effectiveness for the nominated use and highlighted gaps in physicochemical characterisation, immunogenicity and safety information

Studies have shown that bevacizumab, as a VEGF inhibitor, has demonstrated neuroprotective effects in several models of TBI (Genovese and Impellizzeri 2022)

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These results project that retatrutide may have a greater efficacy than tirzepatide and semaglutide due to its triple action at GLP-1, GIP, and glucagon receptors

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