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In the present study, we found largely similar acute subjective effects among female and male participants

Although not evaluated here, lower intracellular GSH levels would also deactivate the GSH-dependent GPX4, further enhancing ferroptotic cell death (8, 38)

A., Sabiwalsky, A., Peters, T., Sulyok, S., Dissemond, J., Schauen, M., Krieg, T., Wirth, T., Simmet, T., and Scharffetter-Kochanek, K

In addition, many important issues need to be further explored, such as the mechanism of the superimposed effect and its safety when polyphenols are applied in combination, the possible interactions with other chemotherapeutic agents such as 5 - fluorouracil, paclitaxel analogs, gemcitabine, pemetrexed, etc., as well as whether oral polyphenols have an impact on ototoxicity by regulating the intestinal flora

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