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Mechanistically, CRAT overexpression markedly increased the proportion of OC cells in G1 phase and decreased the proportion of OC cells in S phase, indicating an induction of G1-S cell cycle arrest (Fig

To better understand the effects of ABHD11 inhibition in CD8 + T cells, we undertook RNA-seq analysis following ML226 treatment

The motor symptoms of PD include bradykinesia, rigidity, and resting tremor associated with disruption of dopaminergic neurons in the substantia nigra

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P-selectin/PSGL-1 inhibitors are currently in clinical development as therapeutic agents to reduce inflammation and pathologic thrombosis (123)