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Consult a healthcare professional if you're using other medications, especially those applied to the scalp

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3.5 CB-839 induces autophagy in CLL cell lines Because glutamine flux regulates mammalian target of rapamycin complex 1s kinase activity, which is responsible for autophagy, we assessed the effects of glutaminase inhibition on autophagy as an alternative mechanism of CB-839mediated cell death ( Figure 4A )

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Upregulation of CHAC1 has been consistently observed in models of retinal damage, kidney and liver injury and heat shockinduced oxidative stress, often in tandem with ER stress (Liu et al., 2023)

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